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Stevens-Johnson syndrome (SJS) is a rare but severe condition that primarily affects the skin and mucous membranes. It often begins with flu-like symptoms, followed by a painful, blistering rash that spreads across the body. The cause of SJS is a reaction to certain medications, including specific epilepsy drugs, antibiotics, and anti-inflammatory painkillers. On occasion, infections such as the cold or flu, cold sores, and glandular fever can trigger SJS in children.
In Mumbai, Stevens-Johnson syndrome specialists encounter numerous cases year-round. At Apollo Hospitals Mumbai, a dedicated team of Stevens-Johnson syndrome treatment doctors are experienced in diagnosing and managing this complex disorder. They are well-equipped to provide comprehensive patient care.
This syndrome can be broadly categorised into two main categories:
Stevens-Johnson Syndrome (SJS): Characterised by inflammation affecting less than 10% of the body's surface area.
Toxic Epidermal Necrolysis (TEN): A more severe form where lesions cover about one-third or more of the body.
SJS presents various symptoms that include:
Fever, sore throat, cough, joint pain and fatigue
A red or purple rash that starts on the face and chest, turns into painful blisters
Blisters on the skin and mucous membranes
Skin shedding occurs shortly after blisters emerge
Swelling of the tongue, lips, face, throat, or mouth
Stevens-Johnson syndrome treatment doctors can use the following tests to diagnose SJS:
Skin Biopsy: A skin biopsy may be performed to examine tissue samples under a microscope.
Histopathological Examination: This involves analyzing tissue samples from affected areas to assess the extent of epidermal necrosis and other pathological changes.
Complete Blood Count (CBC): A CBC may reveal abnormalities such as leukopenia (low white blood cell count), thrombocytopenia (low platelet count), or anaemia, which can be associated with severe drug reactions like SJS.
Immunological Studies: Testing for specific antibodies or markers of immune system activation, such as elevated levels of cytokines or autoantibodies, can help support the diagnosis of SJS.
Skin Patch Testing: Patch testing may be used to identify potential triggers or culprits, such as medications or allergens, that could have provoked the SJS reaction in the first place.
At Apollo Hospitals Mumbai, the best doctors for Stevens-Johnson syndrome treatment offer various options to treat it, comprising:
Hospitalisation: Patients are admitted to the hospital under the care of Stevens-Johnson syndrome surgeon doctors for immediate medical care.
Stopping Nonessential Medications: The first step in treatment is to halt any medications that may have triggered the reaction.
Supportive Care: Involves fluid replacement and nutrition through a nasogastric tube and wound care using cool, wet compresses.
Medications: Such as intravenous immunoglobulins and corticosteroids are given to modulate the immune response.
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H1 | Abacavir: Uses, Dosage, Side Effects, and More |
H2 | What is Abacavir? |
H2 | Uses of Abacavir |
H2 | Dosage and Administration |
H3 | Important Considerations |
H2 | Side Effects |
H3 | Common Side Effects |
H3 | Serious Side Effects |
H2 | Interaction with Other Medicines |
H3 | Benefits of Abacavir |
H2 | Frequently Asked Questions |
H2 | Brand Names |
H2 | Conclusion |
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