Roux-en-Y gastric bypass (RYGB) is a combined restrictive and malabsorptive procedure. It involves creating a small gastric pouch and rerouting the small intestine to form a Y-configuration. This limits food intake and reduces nutrient absorption. RYGB leads to significant weight loss and improvement in obesity-related comorbidities, particularly type 2 diabetes. The procedure is typically performed laparoscopically and takes about 1.5 hours. RYGB requires lifelong nutritional supplementation and follow-up due to the risk of vitamin and mineral deficiencies.