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Sickle cell anaemia is a genetic blood disorder that alters the shape and functionality of red blood cells. A mutation in the haemoglobin gene induces the production of abnormal haemoglobin, termed haemoglobin S. This mutation causes red blood cells to become rigid and sickle-shaped, as opposed to their normal flexible, disc-like shape. This transition leads to various complications, including severe pain crises, anaemia and increased susceptibility to infections.
In the bustling city of Mumbai, with its diverse population, it's not uncommon to encounter individuals grappling with this condition. Fortunately, in this cosmopolitan city, Apollo Hospitals Mumbai has some of the best doctors for sickle cell anaemia treatment.
Sickle cell anaemia has several types, which include:
Haemoglobin SS Disease: A most common and severe form of sickle cell anaemia.
Haemoglobin SC Disease: This is a slightly milder variant.
Haemoglobin SB+ (beta) Thalassemia: This type involves less severe anaemia.
Haemoglobin SB 0 (beta-zero) Thalassemia: This one presents with a more serious form of anaemia.
Individuals with sickle cell anaemia often experience:
Frequent attacks of severe pain known as sickle cell crises
Anaemia, leading to fatigue and weakness
Swelling in hands and feet
Increased susceptibility to infections
Stroke in severe cases
A haematology specialist for sickle cell anaemia may recommend the following to confirm its diagnosis:
Blood Tests: These are used to check for the presence of haemoglobin S, the abnormal haemoglobin associated with sickle cell disease. A complete blood count (CBC) can also provide valuable information about the overall health of the blood.
Haemoglobin Electrophoresis: This test separates different types of haemoglobin based on their electrical charge. It can identify the presence of abnormal haemoglobins, such as haemoglobin S, C, E, and others, helping in diagnosing various haemoglobin disorders.
High-Performance Liquid Chromatography (HPLC): This advanced technique provides a detailed analysis of the different types of haemoglobin present in the blood. It is more precise and can quantify the amount of each type of haemoglobin, making it useful for both diagnosis and monitoring the treatment of hemoglobinopathies.
At Apollo Hospitals Mumbai, doctors for sickle cell anaemia disease treatment employ a range of strategies, including:
Bone Marrow Transplants: This procedure replaces the faulty sickle-shaped red cells with healthy ones from a donor.
Medications: Hydroxyurea, folic acid supplements, and penicillin are recommended by doctors for treating sickle cell anaemia to manage the disease.
Blood Transfusions: These help replace faulty red blood cells, alleviating symptoms and improving blood flow.
Gene Therapy: A cutting-edge treatment modulates the genetic code to produce healthy haemoglobin, potentially providing a cure.
Apollo Hospitals Mumbai boasts experienced doctors for sickle cell anaemia and state-of-the-art medical facilities. Thus, it stands as a reliable choice for those seeking effective treatment.
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H1 | Abacavir: Uses, Dosage, Side Effects, and More |
H2 | What is Abacavir? |
H2 | Uses of Abacavir |
H2 | Dosage and Administration |
H3 | Important Considerations |
H2 | Side Effects |
H3 | Common Side Effects |
H3 | Serious Side Effects |
H2 | Interaction with Other Medicines |
H3 | Benefits of Abacavir |
H2 | Frequently Asked Questions |
H2 | Brand Names |
H2 | Conclusion |
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